Dust models post-Planck: constraining the far-infrared opacity of dust in the diffuse interstellar medium

We compare the performance of several dust models in reproducing the dust spectral energy distribution (SED) per unit extinction in the diffuse interstellar medium (ISM). We use our results to constrain the variability of the optical properties of big grains in the diffuse ISM, as published by the Planck collaboration. We use two different techniques to compare the predictions of dust models to data from the Planck HFI, IRAS and SDSS surveys. First, we fit the far-infrared emission spectrum to recover the dust extinction and the intensity of the interstellar radiation field (ISRF). Second, we infer the ISRF intensity from the total power emitted by dust per unit extinction, and then predict the emission spectrum. In both cases, we test the ability of the models to reproduce dust emission and extinction at the same time. We identify two issues. Not all models can reproduce the average dust emission per unit extinction: there are differences of up to a factor $\sim2$ between models, and the best accord between model and observation is obtained with the more emissive grains derived from recent laboratory data on silicates and amorphous carbons. All models fail to reproduce the variations in the emission per unit extinction if the only variable parameter is the ISRF intensity: this confirms that the optical properties of dust are indeed variable in the diffuse ISM. Diffuse ISM observations are consistent with a scenario where both ISRF intensity and dust optical properties vary. The ratio of the far-infrared opacity to the $V$ band extinction cross-section presents variations of the order of $\sim20\%$ ($40-50\%$ in extreme cases), while ISRF intensity varies by $\sim30\%$ ($\sim60\%$ in extreme cases). This must be accounted for in future modelling.Comment: A&A, in pres

Physical properties of a very diffuse HI structure at high Galactic latitude

The main goal of this analysis is to present a new method to estimate the physical properties of diffuse cloud of atomic hydrogen observed at high Galactic latitude. This method, based on a comparison of the observations with fractional Brownian motion simulations, uses the statistical properties of the integrated emission, centroid velocity and line width to constrain the physical properties of the 3D density and velocity fields, as well as the average temperature of HI. We applied this method to interpret 21 cm observations obtained with the Green Bank Telescope of a very diffuse HI cloud at high Galactic latitude located in Firback North 1. We first show that the observations cannot be reproduced solely by highly-turbulent CNM type gas and that there is a significant contribution of thermal broadening to the line width observed. To reproduce the profiles one needs to invoke two components with different average temperature and filling factor. We established that, in this very diffuse part of the ISM, 2/3 of the column density is made of WNM and 1/3 of thermally unstable gas (T ~2600 K). The WNM gas is mildly supersonic (~1) and the unstable phase is definitely sub-sonic (~0.3). The density contrast (i.e., the standard deviation relative to the mean of density distribution) of both components is close to 0.8. The filling factor of the WNM is 10 times higher that of the unstable gas, which has a density structure closer to what would be expected for CNM gas. This field contains a signature of CNM type gas at a very low level (N_H ~ 3 x 10^19) which could have been formed by a convergent flow of WNM gas.Comment: 13 pages, 12 figures, accepted for publication in A&

An Imprint of Molecular Cloud Magnetization in the Morphology of the Dust Polarized Emission

We describe a morphological imprint of magnetization found when considering the relative orientation of the magnetic field direction with respect to the density structures in simulated turbulent molecular clouds. This imprint was found using the Histogram of Relative Orientations (HRO): a new technique that utilizes the gradient to characterize the directionality of density and column density structures on multiple scales. We present results of the HRO analysis in three models of molecular clouds in which the initial magnetic field strength is varied, but an identical initial turbulent velocity field is introduced, which subsequently decays. The HRO analysis was applied to the simulated data cubes and mock-observations of the simulations produced by integrating the data cube along particular lines of sight. In the 3D analysis we describe the relative orientation of the magnetic field $\mathbf{B}$ with respect to the density structures, showing that: 1.The magnetic field shows a preferential orientation parallel to most of the density structures in the three simulated cubes. 2.The relative orientation changes from parallel to perpendicular in regions with density over a critical density $n_{T}$ in the highest magnetization case. 3.The change of relative orientation is largest for the highest magnetization and decreases in lower magnetization cases. This change in the relative orientation is also present in the projected maps. In conjunction with simulations HROs can be used to establish a link between the observed morphology in polarization maps and the physics included in simulations of molecular clouds.Comment: (16 pages, 11 figures, submitted to ApJ 05MAR2013, accepted 07JUL2013

Direct Estimate of Cirrus Noise in Herschel Hi-GAL Images

In Herschel images of the Galactic plane and many star forming regions, a major factor limiting our ability to extract faint compact sources is cirrus confusion noise, operationally defined as the "statistical error to be expected in photometric measurements due to confusion in a background of fluctuating surface brightness". The histogram of the flux densities of extracted sources shows a distinctive faint-end cutoff below which the catalog suffers from incompleteness and the flux densities become unreliable. This empirical cutoff should be closely related to the estimated cirrus noise and we show that this is the case. We compute the cirrus noise directly, both on Herschel images from which the bright sources have been removed and on simulated images of cirrus with statistically similar fluctuations. We connect these direct estimates with those from power spectrum analysis, which has been used extensively to predict the cirrus noise and provides insight into how it depends on various statistical properties and photometric operational parameters. We report multi-wavelength power spectra of diffuse Galactic dust emission from Hi-GAL observations at 70 to 500 microns within Galactic plane fields at l= 30 degrees and l= 59 degrees. We find that the exponent of the power spectrum is about -3. At 250 microns, the amplitude of the power spectrum increases roughly as the square of the median brightness of the map and so the expected cirrus noise scales linearly with the median brightness. Generally, the confusion noise will be a worse problem at longer wavelengths, because of the combination of lower angular resolution and the rising power spectrum of cirrus toward lower spatial frequencies, but the photometric signal to noise will also depend on the relative spectral energy distribution of the source compared to the cirrus.Comment: 4 pages (in journal), 3 figures, Astronomy and Astrophysics, accepted for publication 13 May 201

Statistical properties of dust far-infrared emission

The description of the statistical properties of dust emission gives important constraints on the physics of the interstellar medium but it is also a useful way to estimate the contamination of diffuse interstellar emission in the cases where it is considered a nuisance. The main goals of this analysis of the power spectrum and non-Gaussian properties of 100 micron dust emission are 1) to estimate the power spectrum of interstellar matter density in three dimensions, 2) to review and extend previous estimates of the cirrus noise due to dust emission and 3) to produce simulated dust emission maps that reproduce the observed statistical properties. The main results are the following. 1) The cirrus noise level as a function of brightness has been previously overestimated. It is found to be proportional to instead of ^1.5, where is the local average brightness at 100 micron. This scaling is in accordance with the fact that the brightness fluctuation level observed at a given angular scale on the sky is the sum of fluctuations of increasing amplitude with distance on the line of sight. 2) The spectral index of dust emission at scales between 5 arcmin and 12.5 degrees is =-2.9 on average but shows significant variations over the sky. Bright regions have systematically steeper power spectra than diffuse regions. 3) The skewness and kurtosis of brightness fluctuations is high, indicative of strong non-Gaussianity. 4) Based on our characterization of the 100 micron power spectrum we provide a prescription of the cirrus confusion noise as a function of wavelength and scale. 5) Finally we present a method based on a modification of Gaussian random fields to produce simulations of dust maps which reproduce the power spectrum and non-Gaussian properties of interstellar dust emission.Comment: 13 pages, 13 figures. Accepted for publication in A&

Adverse Childhood Experiences and the Risk of Coronary Heart Disease in Adulthood: Examining Potential Psychological, Biological, and Behavioral Mediators in the Whitehall II Cohort Study.

BACKGROUND: This study investigated potential psycho‐bio‐behavioral mediators of the association between adverse childhood experiences (ACEs) and the risk of coronary heart disease (CHD) in adulthood. METHODS AND RESULTS: Participants were 5610 British civil servants (mean age, 55.5; 28% women) from the Whitehall II cohort study without CHD at baseline in 1997 to 1999 (wave 5) when retrospective data on the number of ACEs were collected via questionnaire (range, 0–8). Potential mediators assessed at wave 5 included depression and anxiety symptoms, health behaviors (smoking, alcohol dependence, sleep, and physical activity), and cardiometabolic dysregulations. New diagnoses of CHD (myocardial infarction, definite angina, coronary artery bypass grafting, or percutaneous transluminal coronary angioplasty) were assessed from wave 6 (2001) to wave 11 (2012–2013). Logistic regressions examined associations between ACEs, potential mediators, and CHD during the follow‐up period. Natural indirect effects were examined using mediation analysis. A total of 566 (10.1%) participants developed CHD during the follow‐up period. ACEs were associated with an increased likelihood of CHD (odds ratio per ACE, 1.09; 95% CI, 1.00–1.19). Controlling for age and sex, mediation analyses revealed an indirect effect of depression symptoms (natural indirect effects, 1.05; 95% CI, 1.03–1.07), anxiety symptoms (natural indirect effects, 1.12; 95% CI, 1.10–1.15), and a greater number of cardiometabolic dysregulations (natural indirect effects, 1.02; 95% CI, 1.01–1.03) in the association between ACEs and incident CHD. Behavioral factors were not statistically significant mediators. CONCLUSIONS: Depression symptoms, anxiety symptoms, and cardiometabolic dysregulations partially mediated the association between ACEs and CHD. Regular screening and treatment of symptoms of psychological disorders and cardiometabolic dysregulations may help mitigate the long‐term health burden of ACEs

Low-Velocity Halo Clouds

Models that reproduce the observed high-velocity clouds (HVCs) also predict clouds at lower radial velocities that may easily be confused with Galactic disk (|z| < 1 kpc) gas. We describe the first search for these low-velocity halo clouds (LVHCs) using IRAS data and the initial data from the Galactic Arecibo L-band Feed Array survey in HI (GALFA-HI). The technique is based upon the expectation that such clouds should, like HVCs, have very limited infrared thermal dust emission as compared to their HI column density. We describe our 'displacement-map' technique for robustly determining the dust-to-gas ratio of clouds and the associated errors that takes into account the significant scatter in the infrared flux from the Galactic disk gas. We find that there exist lower-velocity clouds that have extremely low dust-to-gas ratios, consistent with being in the Galactic halo - candidate LVHCs. We also confirm the lack of dust in many HVCs with the notable exception of complex M, which we consider to be the first detection of warm dust in HVCs. We do not confirm the previously reported detection of dust in complex C. In addition, we find that most Intermediate- and Low-Velocity clouds that are part of the Galactic disk have a higher 60 micron/100 micron flux ratio than is typically seen in Galactic HI, which is consistent with a previously proposed picture in which fast-moving Galactic clouds have smaller, hotter dust grains.Comment: 30 pages, 7 figures. Accepted to the Ap

Intracellular Transport, Assembly, and Degradation of Wild-Type and Disease-linked Mutant Gap Junction Proteins

More than 130 different mutations in the gap junction integral plasma membrane protein connexin32 (Cx32) have been linked to the human peripheral neuropathy X-linked Charcot–Marie–Tooth disease (CMTX). How these various mutants are processed by the cell and the mechanism(s) by which they cause CMTX are unknown. To address these issues, we have studied the intracellular transport, assembly, and degradation of three CMTX-linked Cx32 mutants stably expressed in PC12 cells. Each mutant had a distinct fate: E208K Cx32 appeared to be retained in the endoplasmic reticulum (ER), whereas both the E186K and R142W mutants were transported to perinuclear compartments from which they trafficked either to lysosomes (R142W Cx32) or back to the ER (E186K Cx32). Despite these differences, each mutant was soluble in nonionic detergent but unable to assemble into homomeric connexons. Degradation of both mutant and wild-type connexins was rapid (t1/2 \u3c 3 h) and took place at least in part in the ER by a process sensitive to proteasome inhibitors. The mutants studied are therefore unlikely to cause disease by accumulating in degradation-resistant aggregates but instead are efficiently cleared from the cell by quality control processes that prevent abnormal connexin molecules from traversing the secretory pathway

A New Galactic Extinction Map of the Cygnus Region

We have made a Galactic extinction map of the Cygnus region with 5' spatial resolution. The selected area is 80^\circ to 90^\circ in the Galactic longitude and -4^\circ to 8^\circ in the Galactic latitude. The intensity at 140 \mum is derived from the intensities at 60 and 100 \mum of the IRAS data using the tight correlation between 60, 100, and 140 \mum found in the Galactic plane. The dust temperature and optical depth are calculated with 5' resolution from the 140 and 100 \mum intensity, and Av is calculated from the optical depth. In the selected area, the mean dust temperature is 17 K, the minimum is 16 K, and the maximum is 30 K. The mean Av is 6.5 mag, the minimum is 0.5 mag, and the maximum is 11 mag. The dust temperature distribution shows significant spatial variation on smaller scales down to 5'. Because the present study can trace the 5'-scale spatial variation of the extinction, it has an advantage over the previous studies, such as the one by Schlegel, Finkbeiner, & Davis, who used the COBE/DIRBE data to derive the dust temperature distribution with a spatial resolution of 1^\circ. The difference of Av between our map and Schlegel et al.'s is \pm 3 mag. A new extinction map of the entire sky can be produced by applying the present method.Comment: 27 pages, 14 figures, accepted for publication in Ap